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ike comments on Open thread, Aug. 03 - Aug. 09, 2015 - Less Wrong Discussion
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In this case it seems like the marginal value of blood donation should be roughly what the organizations like the red cross are willing to pay to get additional blood donations.
You could look at how often patients get less blood because of supply issues.
That is briefly mentioned in the post, and in more detail in the comments.
It does depend on certain efficiency assumptions about the Red Cross, though.
If you don't believe that the Red Cross is doing a good job on this then research it's actual practice and openly criticising it could be high leverage. There enough money in the medical system to pay a reasonable price for the blood that's needed.