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Tem42 comments on Nature publishes an article about alternative therapy - Less Wrong Discussion
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I do not take pills with water, but I have found that water, Emergen-C, and oral rehydration fluid do help in some cases, and I highly recommend them.
As far as I can tell, dehydration is a contributing cause to my headaches, but not the primary cause. Unsurprisingly, liquids help the most after I have been exercising.