ChristianKl comments on Estimate the Cost of Immortality - Less Wrong Discussion
You are viewing a comment permalink. View the original post to see all comments and the full post content.
You are viewing a comment permalink. View the original post to see all comments and the full post content.
Comments (115)
I don't think that all of the increased lifespan is due to healthcare spending. Various enviromental regulation likely increased lifespan. Our current paradigm of drug development unfortunately get's exponentially more expensive via Eroom's law. I doubt that simply spending more money in the same way produces linear progress.
I think the problem of the mythical man month also exists in research. You can't simply throw in more money. Given researchers money can often make them spend money on fancy equipment instead of thinking hard about what to do.
As far as hopes for the future of biology goes, I hope that Theranos will introduce something like Moore's law into blood testing prices. If it succeeds with that mission it's not simply because there a lot of money thrown into blood testing but because Theranos focus on producing cheap blood testing while currently the companies in the market have no incentives to test cheaply.
YCombinators turn to fund biotech companies also fills me with hope. Bikanta Nanodiamond technology that allows very high resultion imaging of anything that you can hit with an antibody fills me with hope. The promise 100X more precise cancer imaging but if their technology really works and the can do it cheap, it has application beyond just cancer because being able to image anything at high resolution will allow us to learn to tag a lot of different things with antibodies. You could tag drugs with the nanodiamonds to see where in the body the drug travels.
The fact that nanodiamonds are a solution also suggests that simply moving all research dollars to biology would be bad because nanodiamonds needed a lot of physics research to become viable. Better signal processing algorithms and AI might also further increase the precision of their imaging.
Another great biotech company founded by YCombinator is uBiome. Thanks to relatively cheap DNA sequencing they track bacteria population on skin/mouth/gut/nose and penis/vagina. At present sequencing prices their technology isn't mass market compatible but if sequencing prices continue to drop at rates of Moore's law or faster than Moore's law we will have a new area of medicine. In 20 years we might all consciously repopulate our bacteria populations.
Isn't Theranos currently going down in flames?
Why wouldn't they have such incentive? It seems that Theranos could offer prices much lower than the market price because Theranos tests were much less accurate than standard medical tests, perhaps to the point of outright fraud.
There a lot of money currently invested in attacking Theraros. That's no indication that the company has a problem but that it threatens established interests.
A company for that's true wouldn't lobby for the FDA to regulate their tests. Nothing that happened indicates that Theranos believes that they aren't confident that the FDA will approve their test.
Prices are fixed by the Medicare reinbursement rate and other insurance companies paying that rate. Lab companies in the existing market can't win by offering lower prices than their competitors. That changes through the direct to consumer sales that Theranos is doing.
At the point where the governments believes tests can be done more cheaply they reduce reinbrusements rates. As a result the labs don't focus on developing technogy to get cheaper testing and the basic way testing is done is the same at it was four decades. They have incentives to develop better tests and tests for new things but they don't have real incentives to reduce the prices.
Theranos is completely right in their lobbying agenda of pushing for direct to consumer sales to produce a functioning marketplace and push for patients rights to see the exact results of their medical tests while asking the FDA to regulate them.