We're talking about a guy who wants to live forever, so it's difficult to make a case that someone like Eliezer would be negligent toward his own health. Given his previous record of thinking hard about hard problems, I find it more likely that he has already tried his best at this problem and found a compromise that acknowledges the way his body works and does not interfere with whatever other goals matter more to him. But even this extremely cautious way to describe it still sounds to me like a disrespectful intrusion into a stranger's life choices. I understand how discipline and self-control are related to good rationalist habits, but this kind of discussions always run the risk to degenerate into fat-shaming.