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4.You have a neurodegenerative disease, you can survive for years but if you wait there will be little left to preserve by the time your heart stops.
I saw that as falling under #3. There are treatments for dementia and Alzheimer's but they all suck and one can rationally prefer the risk of immediate death to losing it all. This comes up a lot linked with assisted-suicide, as does the attendant legal risks for oneself and the cryonics org (some of Mike Darwin's blog touches on the effects of aging, and I think Ettinger himself took the dehydration route a few years ago).