johnlawrenceaspden comments on Thyroid Hormones, Chronic Fatigue and Fibromyalgia: A Hypothesis and a Proposed Experiment - Less Wrong Discussion
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I agree with all of that, although I haven't read Pettle (yet!). My current best guess would be synthetic T3:T4 1:10 as a good starting point for adjustments, but I really think that the alternative people may be making some good points, and I think we should try what they say, see whether it works, and then start fiddling.