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turchin comments on The map of nanotech global catastrophic risks - Less Wrong Discussion
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I think that all kinds of nanoparticles are appearing naturally in the form of smoke and dust. It is known to be unhealthy, but nothing like existential risk. Smoking cigarets is known to damage brain, but it is not a grey goo.
I included prions in another my map biological risks, here: http://lesswrong.com/r/discussion/lw/nbw/the_map_of_global_catastrophic_risks_connected/