You're looking at Less Wrong's discussion board. This includes all posts, including those that haven't been promoted to the front page yet. For more information, see About Less Wrong.

johnlawrenceaspden comments on The Thyroid Madness : Core Argument, Evidence, Probabilities and Predictions - Less Wrong Discussion

10 Post author: johnlawrenceaspden 14 March 2016 01:41AM

You are viewing a comment permalink. View the original post to see all comments and the full post content.

Comments (132)

You are viewing a single comment's thread. Show more comments above.

Comment author: johnlawrenceaspden 18 March 2016 10:15:45PM *  0 points [-]

No, I didn't mean a "let's meet for tea and share sob stories" group, I meant if we had 3-4 talented individuals with CFS and a pro-rationality mindset, it may be worth trying to see whether we can easily nudge the medical community into trying to seriously investigate the HPA/thyroid angle on CFS.

Ah, OK, well, that is what I am trying to do. And at the moment my principal difficulty is that I don't believe it myself. I reckon if I can grub up enough evidence to make myself believe it then making medical types believe it will not be too hard.

So if you'd like to join the effort, go scour me the medical literature for evidence that Central Sensitivity Syndrome sufferers have low basal metabolic rates, endocrine hormone resistances, or low peripheral temperatures after they have been asleep for a long time.

Or evidence against any of those things. There is no point wasting anyone's time with a good idea that is false.

Google Scholar, Pubmed (http://www.ncbi.nlm.nih.gov/pubmed), and sci-hub.io are very useful, as is membership of a university which subscribes to journals. But even better if you can think of tools I'm not using. I am new to this. When I were a lad you had to write to the authors if you wanted a copy.

And if you find an interesting paper, you can look on google scholar for other papers citing it, and see what they say. That is the sum total of my search skillz. I need the help of a proper academic.

And by the way, I don't actually think I've got CFS! It's just one of the possibilities. But I see people claiming the glory of physics without using the methods of science. And for some reason I find that very motivating.

Comment author: johnlawrenceaspden 18 March 2016 10:23:33PM 0 points [-]

Also, I'm currently thinking, thyroid controls basal rate, adrenal controls rate minute-by-minute. So stick to your guns, adrenal wise, and tell me the obvious things I've missed.