As yet we have ~zero evidence for being in a simulation.
We have evidence (albeit no "smoking-gun evidence") for eternal inflation, we have evidence for a flat and thus infinite universe, string theory is right now our best guess at what the theory of everything is like; these all predict a multiverse where everything possible happens and where somebody should thus be expected to simulate you.
Your odds of waking up in the hands of someone extremely unfriendly is unchanged. You're just making it more likely that one fork of yourself might wake up in friendly hands.
Well, I think that qualifies. Our language is a bit inadequate for discussing situations with multiple future selves.
I find that about as convincing as "if you see a watch there must be a watchmaker" style arguments.
There are a number of ways theorized to test if we're in various kinds of simulation and so far they've all turned up negative.
String theory is famously bad at being usable to predict even mundane things even if it is elegant and "flat" is not the same as "infinite".
Wait But Why published an article on cryonics:
http://waitbutwhy.com/2016/03/cryonics.html