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gjm comments on Newcomb versus dust specks - Less Wrong Discussion
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Then for the "smoking lesion" problem to be any use to you, you need to perform a sort of mental translation in which it isn't about smoking but about some other (perhaps imaginary) activity that you do enjoy but is associated with harmful outcomes. Maybe it's eating chocolate and the harmful outcome is diabetes. Maybe it's having lots of sex and the harmful outcome is syphilis. Maybe it's spending all your time sitting alone and reading and the harmful outcome is heart disease. The important thing is to keep the structure of the thing the same: doing X is associated with bad outcome Y, it turns out (perhaps surprisingly) that this is not because X causes Y but because some other thing causes both X and Y, you find yourself very much wanting to do X, so now what do you do?
Having a smoking lesion make you choose smoking is vague. Does it make you choose smoking by increasing the utility you gain from smoking, but not affecting your ability to reason based on this utility? Or does it make you choose smoking by affecting your ability to do logical reasoning?
In the former case, switching from nonsmoking to smoking because you made a logical conclusion should not affect your chances of dying, even though switching to smoking in general should affect your chance of dying.
In the latter case, switching to smoking should affect your chance of dying, but you are then asking a question which presupposes under some circumstances that you can't answer it.