There used to be recurrent Sequences readthroughs. Basically somebody would just post a link to the next entry in the Sequences and it would sit in Discussion for a week or so and be discussed. I found that re-reading them at a slow and deliberate pace really helped with absorption.
This spaced repetition deck was also somewhat useful, though I don't know if it was quite worth the time investment.
I'm just beginning to go through Rationality: From AI to Zombies. I want to make the most of the lessons contained in the sequences. Usually when I read a book I simply take notes on what seems useful at the time, and a lot of it is forgotten a year later. Any thoughts on how best to internalize the lessons from the sequences?