I'm not sure this response is actually coherent. "Force our own values on the evolutionary process" is probably impossible in principle, as is "decouple ourselves from evolution entirely"; uploading would still result in creatures that would make imperfect imitations of themselves, which would mean still more selection, and even faster than before.
"Consider something a disease if it tends to move us further away from the condition of being composed of a tenuous gas of photons and leptons"... I do not see a real question here, because nothing can tend to move us further away from that condition. We are always moving toward that condition. In fact when we do things that seem better to us, we are usually moving towards it faster, by expending more energy.
"Force our own values on the evolutionary process" is probably impossible in principle
Really? Consider, for a particularly clear-cut instance which I am not especially endorsing, eugenics.
(I don't mean to imply that we could hope to force all our values on the evolutionary process. Any more than evolution can reasonably be said to have, as it were, opinions on most questions of value.)
nothing can tend to move us further away from that condition
We could move towards it faster or slower. Obviously we should blow ourselves up as violently as possible, in order to be more in tune with the Values of the Universe.
It's great to make people more aware of bad mental habits and encourage better ones, as many people have done on LessWrong. The way we deal with weak thinking is, however, like how people dealt with depression before the development of effective anti-depressants:
The only "anti-stupidity drugs" we have are nootropics. But the nootropics we have weren't developed as nootropics. Piracetam was, I think, developed to treat seizures. L-DOPA was developed to treat Parkinson's. No one knows who started using ginkgo biloba or what they used it for; it was used to treat asthma 5000 years ago. Adderall derives from drugs used to keep soldiers awake in World War 2.
And none of them are very good against stupidity. AFAIK, to date, not one drug has been developed by understanding and targeting the causes of different types of stupidity. We have the tools to do this--we could, for instance, sequence a lot of peoples' DNA, give them all IQ tests, and do a genome-wide association study, as a start.
We don't research these things because society doesn't want to research them. People don't conceive of stupidity as a disease that can be cured. We need, somehow, to promote thinking of stupidity as a mental illness. As something drug companies could make billions of dollars off of.