Existential biotech hazard that was designed in the 90s?
Does anyone know something about this alteration of Klebsiella planticola? Paywalled paper here. (If someone has got access please PM me, I would like to read the paper to write a more fleshed out article.)
While I am not convinced that it would really have spread to every terrestrial ecosystem, or even every wheat field and I am not even sure if it could compete successfully with the wild type, I certainly would not bet the world on that. Even if it might only have become a nasty crop bug instead of an ecosystem killer, I think this may be the closest encounter with a true existential risk we have had so far. This suggests, that even our current low end biotech may be the greatest existential risk we face at the moment. Or is this just hyped bullshit for some reason I do not see right now (without reading the paper)?
Edit: Upon reading the original paper I am quite sure Cracked.com greatly exagerated the potential threat. 10^8 cfu (colony formin units) K. planticolata per gram soil (dry weight) was added on day 0, but after 8 weeks only 10^2 cfu survived (this is true for both wild type and modified K. planticolata). This suggests, that K. planticolata in the wild has typical densities more like 10^2 cfu per g than 10^8 cfu per g. 10^2 cfu per g is nowhere near enough to produce lethal ethanol concentrations in the soil, even if the modified strain could compete in the wild. Furthermore the concentration of the modified K. planticolata decreased faster than the concentration of the wild type suggesting reduced fitness of the GMO. On the other hand after 8 weeks both K. planticolata strains arrived at the same density of 100 cfu per g indicating comparable medium term survivability in unsterilized soil (I am not sure if indigenous K. planticolata which could compete with the GMO was present in the soil sample used). Yes, they did avoid the obvious failure mode of not differentiating between wild type and modified K. planticolata during recovery of K. planticola strains from the samples.
How does remote Joule heating of carbon nanotubes advance singularity timelines?
Carbon nanotubes: The weird world of 'remote Joule heating'
Minimizing Joule heating remains an important goal in the design of electronic devices1, 2. The prevailing model of Joule heating relies on a simple semiclassical picture in which electrons collide with the atoms of a conductor, generating heat locally and only in regions of non-zero current density, and this model has been supported by most experiments. Recently, however, it has been predicted that electric currents in graphene and carbon nanotubes can couple to the vibrational modes of a neighbouring material3, 4, heating it remotely5. Here, we use in situ electron thermal microscopy to detect the remote Joule heating of a silicon nitride substrate by a single multiwalled carbon nanotube. At least 84%of the electrical power supplied to the nanotube is dissipated directly into the substrate, rather than in the nanotube itself. Although it has different physical origins, this phenomenon is reminiscent of induction heating or microwave dielectric heating. Such an ability to dissipate waste energy remotely could lead to improved thermal management in electronic devices6."
Carbon nanotubes in biology and medicine: In vitro and in vivo detection, imaging and drug delivery
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