I will break up with my girlfriend at some point over the next year: 60%.
I sincerely hope your girlfriend does not read this site, or at least doesn't know your username.
My girlfriend knows and is highly amused at my pessimism.
My logic is that I have never actually had a relationship that went much beyond the six-month mark, and while there are all kinds of factors that mean that this one is different and will stand the test of time, all of my other relationships also had all kinds of factors that meant this one is different and will stand the test of time.
The prediction is only 60%, however, since I might have actually gotten better at relationships since the last go-round. And because my girlfriend is really fucking awesome. :)
Going through expiring predictions reminded me. Just as we did for 2010 and 2011, it's time for LessWrong to make its beliefs pay rent and give hostages to fortune in making predictions for events in 2012 and beyond.
Suggested topics include: Methods of Rationality updates (eg. "will there be any?"), economic benchmarks (price of gold has been an educational one for me this past year), medical advances (but be careful not to be too optimistic!), personal precommitments (signing up for cryonics?), being curmudgeonly about self-improvement, making daring predictions about the future of AGI, and so on.
As before, please be fairly specific. I intend to put most predictions on PredictionBook.com and it'd be nice if they weren't too hard to judge in the future.
(If you want advice on making good predictions, I've tried to write up a few useful heuristics I've learned. So far in the judging process, I've done pretty well this year, although I'm a little annoyed I got a Yemen prediction right but for the wrong reasons.)