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westward comments on Post ridiculous munchkin ideas! - LessWrong
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Take Wellbutrin (bupropion) for general mood improvement and increased incentive to Get Things Done. Cycling it does seem to be beneficial, as the body will eventually adjust.
Bupropion did nothing for me.
I suspect this is a special case of the general rule "if you have depression, seek appropriate treatment," which is really really good advice.
The low hanging fruit is to read the book Feeling Good, which has been shown to help depression in studies.