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This is not at all an unrealistic possibility. It probably will be via gene knockout rather than a drug injection, if it happens. See Adam Shriver, "Knocking Out Pain in Livestock: Can Technology Succeed Where Morality Has Stalled?"
If this doesn't happen, it will probably be either because lab-grown meat ended up being cheaper to mass-produce, or because the people strongly pushing for animal rights were too squeamish to recognize the value of this option.
Previously discussed here at Overcoming Bias. (I also remember Michael Anissimov responding, but I can't find that.)
Also, you're certainly optimistic about advancing from chickens having a reduced experience of pain to their being undisputedly proven to be happy with all aspects of their experience.