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Carinthium comments on Arguments Against Speciesism - LessWrong
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People get anaesthesia before undergoing surgery and get drunk before risking social embarrassment all the time.
Anaethesia reduces pain, which is the primary reason people take it. Getting drunk reduces inhibitions (which is good if you're trying to do something despite embarrasment), plus you tend not to remember the events afterwards.
EDIT: Just trying to clarify ice9's point here, to be clear.