IME (which is admittedly about a decade out of date at this point), the Boston area as compared to the Bay Area is:
* relatively lighter on the human potential improvement, environmentalism/whole-earth, alternative wellness fronts
* more neo-Pagan than New Age in its spiritual flavor
* relatively heavier on the computer science fronts
* has a significant "actually, working for established companies to do worthwhile things is kind of cool too" component I don't see represented here

That said, "relatively" is a key word. The Boston and Bay Areas are more like each other than either of them are like most of the rest of the country.