"Fanatics may suppose, that dominion is founded on grace, and that saints alone inherit the earth; but the civil magistrate very justly puts these sublime theorists on the same footing with common robbers, and teaches them by the severest discipline, that a rule, which, in speculation, may seem the most advantageous to society, may yet be found, in practice, totally pernicious and destructive." -- David Hume
More of an anti-fanaticism quotation, but it seems to belong.
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"...natural selection built the brain to survive in the world and only incidentally to understand it at a depth greater than is needed to survive. The proper task of scientists is to diagnose and correct the misalignment." -- E. O. Wilson