Andy_McKenzie

When cryoprotectants are perfused through the blood vessels in the brain, they cannot cross the blood-brain barrier as fast as water can move in the opposite direction. And cryoprotectants generally have a much higher osmotic concentration than the typical blood plasma. For example, the cryoprotectant solution M22 has an osmotic...

(Cross-posted from here.) If you read even a tiny bit about brain preservation, you will pretty quickly find people saying things along the lines of “they can’t even freeze a mouse and bring it back to life” and thereby dismissing people in the field as hopelessly deluded. It will not...

People often ask me this. It’s a good question. It seems potentially important for anyone who doesn’t want to die, or doesn’t want other people to have to die. I don’t feel like I have a good answer, which is one reason I want to do more research. But recently...

I first learned about cryonics when I read Eliezer and Robin's posts about it on Overcoming Bias years ago. I got cryopilled. Somewhat amazingly to me, I'm now a researcher in this field. So I thought this community might be interested to know that I was one of several co-authors...

In a new post, Nostalgebraist argues that "AI doomerism has its roots in anti-deathist transhumanism", representing a break from the normal human expectation of mortality and generational change. They argue that traditionally, each generation has accepted that they will die but that the human race as a whole will continue...

The Less Wrong 2023 survey results are out. As usual, it includes some questions about cryonics. One is about what people’s level of interest in cryonics is (not interested, considering, cryocrastinating, signed up, etc.). Another asks about people’s subjective probability of successful restoration to life in the future, conditional on...

Cross-posted from my blog, Neurobiology Notes. John Hunter (1728–1793) did not have an especially promising start to his academic life. He was born the youngest of 10 children to a family living in the countryside near Glasgow. They lived in a two bedroom cottage and the children slept in box...