People with normal weight and higher (exact numbers depend on gender etc.) have a lot of adipose tissue, which absorbs and releases fuel all the time - after every meal there's excess energy, between meals and at nights there's deficit of energy, it actively manages that.
When you eat insufficient amount of food, your body tries to keep your energy in homeostasis by things like:
- increased hunger (strongly countered by ECA)
- decreased energy levels (strongly countered by ECA)
- decreased metabolic rate (somewhat countered by ECA which has minor thermogenic effect)
- increased release of fuel from adipose tissue (what we want, maybe somewhat enhanced by ECA)
- increased breakdown of lean tissue (maybe somewhat countered by ECA, eating relatively higher protein diet may have protective effect here)
Your homeostasis will get what it wants somehow, and ECA tries to prevent it from doing it the way you don't want it to, so it's more or less limited to primarily relying on releasing fuel from adipose tissue. Trying to starve yourself, and willpower the hunger away works much worse than that.
If your adipose tissue cannot do that since it lacks sufficient stored fuel, your body will try the other things harder, and you may have some nasty side effects.
Anyway, who the hell would want to take ECA while being at BMI 18?
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In their search for "true beliefs" they would quickly discover that there is no such thing as "actually true" but that science deals in more and more viable models. So, they would abandon their search for "truth" and would go onward to the search for better and better fitting models. (See definitions of science ... and, for a philosophical point of view, radical constructivism).
Our senses don't perceive the "real" world. They build a highly refined and effective illusion of complete perception. (See for example the blind spot in the eye, the physiology of color perception, or our sense of hearing.
Likewise, our minds always use simplified models. No one would be able to catch a falling ball if he had to actually calculate the flight curve - yet, even children are able to do it. That's because if you keep your eyes fixed at the ball and have to lower your head in a constant way you are standing at the right spot to catch the ball. (If your rate of head-lowering is slower you have to move till it is.)
So, doing the actual calculations would be a waste of time, because there's a simpler way to catch a ball.
Even if one uses always the best and newest models science provides, you will never, ever be really at the frontier because so many papers are published every day. And even if one could, scientists are able to err. And do so frequently.
(See for example selection bias. There are LOTS of papers about it.)
So, someone on a quest to find "truth" is a romantic twerp who will accomplish nothing, because he will expect to find something static and final. Science and understanding are processes.
The only fields of human endeavor where you find "truth" are mathematics and religion.
(Most things I mention in this article are findable in the wikipedia. If you don't understand, look them up. Everyone should now about scientific models, "truth" and constructivsm. Oh, and the physiology of our senses.)