Disclaimer: Only spent 20 minutes on this, so it might be incomplete, or you may already have addressed some of the following points:

At first glance, John Lowe authored 2 pubmed-listed papers on the topic.

The first of which in an open journal with no peer review (Med. Hypotheses) which has also published stuff on e.g. AIDS denialism. From his paper: "We propose that molecular biological methods can provide confirmatory or contradictory evidence of a genetic basis of euthyroid FS [Fibromyalgia Syndrome]." That's it. Proposing a hypothesis, not providing experimental evidence, paper ends.

The second paper was published in a somewhat controversial low impact journal (at least peer-reviewed). However, this apparently one and only peer reviewed and published paper actually contradicts the expected results, Lowe pulls off a somewhat convoluted move to save his hypothesis:

"TSH, FT3, or FT4 did not correlate with RMR [Resting Metabolic Rate] values. For two reasons, however, ITHR [Inadequate Thyroid Hormone Regulation] cannot be ruled out as the mechanism of FM [Fibromyalgia] patients’ lower RMRs: (1) TSH, FT3 , and FT4 levels have not been shown to reliably correlate with RMR values, and (2) these tests evaluate only pituitary-thyroid axis function and cannot rule out central HO and PRTH."

Yea ...

In addition, lots of crank signs: Lowe's review from 2008, along with his other writings, is "published" in a made-up "journal" which still lists him (from beyond the grave, apparently) as the editor-in-chief.

No peer review, pretending to be an actual journal, a plethora of commercial sites citing him and his research ... honi soit qui mal y pense!

AlphaGo system won first game. Not a go player, but the commentary I've seen suggests it was quite close until the very end.

Hypothesis 1: The cluster plays to maximize odds of a win, not magnitude of a win, and is exploiting a class of close wins that humans have a hard time with. Expect sweeping near wins.

Hypothesis 2: The cluster and the champion are indeed evenly matched. Expect wins and losses. May imply that the game saturates at high levels of analysis, and that there is no such thing as a 'superhuman' go player because the best humans hit the point of diminishing returns.

*EDIT: evidence accumulating in favor of #1.

*EDIT2: final results suggest something between the two.

Please don't spam the same comment to different threads.

That seems extremely dangerous.

LOL. Word inflation strikes again with a force of a million atomic bombs! X-)

Are you really arguing for keeping ideologically incorrect people barefoot and pregnant, lest they harm themselves with any tools they might acquire?

As seen in the first episode series Caprica, quoth Zoe Graystone:

"(...) the information being held in our heads is available in other databases. People leave more than footprints as they travel through life; medical scans, dna profiles, psych evaluations, school records, emails, recording, video, audio, cat scans, genetic typing, synaptic records, security cameras, test results, shopping records, talent shows, ball games, traffic tickets, restaurant bills, phone records, music lists, movie tickets, tv shows... even prescriptions for birth control."

I, for one, think that the meme-mix defining our identity in itself could capture (predict) our behavior in large parts, foregoing biographical minutiae. Bonesaw in Worm didn't need precise memories to recreate the Slaughterhouse Nine clones.

Many think we can zoom out from atoms to a connectome, why not zoom out from a connectome to the memes it implements?

Go on and elaborate, but unless you can show some very thorough technical considerations, I just don't see how you're able to claim a mind has low Kolmogorov complexity.

I did try to look. My browser said "Secure Connection Failed".

Ha:) Is that because we use self-signed SSL cert? Try again. We'll upgrade cert later.

So, all of hyper-equity can be controlled by 1,000 - 10,000 people?

No, as many people as there are problems (Goals). Potentially infinite.

I got waaay too far into this before I realized what you were doing... so well done!

Light touch indeed. They fucked it up so badly

Eh... the story preceding that rebellion argues, if anything, that the Company tried too hard to bend to local practices, and the British public was outraged that "Clemency Canning" didn't want to come down like a hammer on the natives.

RationalWiki discusses a few:

Another problem of LessWrong is that its isolationism represents a self-made problem (unlike demographics). Despite intense philosophical speculation, the users tend towards a proud contempt of mainstream and ancient philosophy[39] and this then leads to them having to re-invent the wheel. When this tendency is coupled with the metaphors and parables that are central to LessWrong's attraction, it explains why they invent new terms for already existing concepts.[40] The compatibilism position on free will/determinism is called "requiredism"[41] on LessWrong, for example, and the continuum fallacy is relabeled "the fallacy of gray." The end result is a Seinfeldesque series of superfluous neologisms.

In my view, RationalWiki cherry picks certain LessWrongers to bolster their case. You can't really conclude that these people represent LessWrong as a whole. You can find plenty of discussion of the terminology issue here, for example, and the way RationalWiki presents things makes it sound like LessWrongers are ignorant. I find this sort of misrepresentation to be common at RationalWiki, unfortunately.