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This is an interesting article-- it's got an overview of what's currently seen as the problems with replicability and fraud, and some material I haven't seen before about handing the same question to a bunch of scientists, and looking at how they come up with their divergent answers.
However, while I think it's fair to say that science is really hard, the article gets into claiming that scientists aren't especially awful people (probably true), but doesnn't address the hard question of "Given that there's a lot of inaccurate science, how much should we trust specific scientific claims?"
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