Yvain asked:

So if you had to design a eugenics program, how would you do it? Be creative.

I'm asking because I'm working on writing about a fictional society that practices eugenics. I want them to be interesting and sympathetic, and not to immediately pattern-match to a dystopia that kills everyone who doesn't look exactly alike.

My reply was too long for LiveJournal, so I'm posting it here:

1. The real step 1 in any program like this would be to buy the 3 best modern textbooks on animal breeding and read them. (My grandfather is a researcher in this field so I'm unusually aware that it exists.)

2. If you give me genetic selection on multiple possible embryos where I can read off the genome of each one, I can do much better, much faster, than if I'm only allowed to look at the mother and father's genome and predict on that basis. If I can only look at the mother and father's relatives and life achievements, I do worse, but modern tech is very rapidly advancing to be able to read off the parents' genome cheaply.

3. If society's utility has a large component for genius production, then you probably want a very diverse mix of different high-IQ genes combined into different genotypes and phenotypes. (Although some recent research suggests that the most important thing for IQ may be avoiding mutational load, i.e., the modal genome would be super-von-Neumann. Even so, we'd want a diverse mix of everything else cognitive that wasn't about modality.)

4. Doing a Bayesian value-of-information calculation on rare alleles and potentially interesting allele combinations will automatically include a value for diversity into your eugenic program, based on the value of promoting a gene / combo in much larger numbers if that gene or gene combo is found to be successful. You would get much *more* interesting diversity in the next generation automatically, as many previously low-frequency alleles were combined in greater numbers and greater diversity than before. *Not* doing a value-of-info calculation accounts for a lot of the dystopic load of alleged dystopias.

5. The obvious basic instrument in a society depicted as well-intentioned would be an economic policy of trying to internalize the externalities of a child, just like a well-intentioned society might try to internalize the externalities of e.g. carbon dio...

OMT

OMT

OMT

OMT