Unfortunately, most of the funds invested to finance people like Norman Borlaug turned out not to be financing Norman Borlaug.
Still, if you want to generalize from that example, feel free. The conclusion would be that would-be effective altruists should be sending their money to the Mexican government, which is what was paying Norman Borlaug to do the work that led to his discoveries. We could generalize further and suggest supporting government-sponsored research. But I don't think there's any credible way to get from Norman Borlaug to saying that the best way to help the world's poorest people is to invest in the stock market or to send money to elite US universities like Harvard, which were your preferred options.
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I don't think Harvard is on any EA list for recommended charities. You also don't provide an argument that Harvard has a high use for marginal dollars and that more EA money should go towards Havard.
My argument is precisely the opposite. My argument is that Harvard is so rich that it has very low use for marginal dollars, but at the same time it has a credible commitment to its future state, so large donations to Harvard will serve to swell its endowment. And also that Harvard has demonstrated the ability to manage its endowment well. Therefore funds donated to Harvard are likely to be invested indefinitely - and therefore to provide increasing amounts of economic tools that will benefit mankind, both now and in the future.