= 27d567bc2d48d9f40e9ccc20ea370b15)
Do you have an opinion about whether Vitamin K2 should be used along with Vitamin D3 supplementation?
In response to
Recent updates to gwern.net (2015-2016)
I happen to be working on that at the office. Here is a snapshot of the opinion landscape (all from PubMed):
Iwamoto J. Vitamin K₂ therapy for postmenopausal osteoporosis. Nutrients. 2014 May 16;6(5):1971-80.
DiNicolantonio JJ, Bhutani J, O'Keefe JH. The health benefits of vitamin K. Open Heart. 2015 Oct 6;2(1):e000300.
Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015 Mar;26(3):1175-86.
Falcone TD, Kim SS, Cortazzo MH. Vitamin K: fracture prevention and beyond. PM R. 2011 Jun;3(6 Suppl 1):S82-7.
Maresz K. Proper Calcium Use: Vitamin K2 as a Promoter of Bone and Cardiovascular Health. Integr Med (Encinitas). 2015 Feb;14(1):34-9.
Hamidi MS, Cheung AM. Vitamin K and musculoskeletal health in postmenopausal women. Mol Nutr Food Res. 2014 Aug;58(8):1647-57.
Stevenson M, Lloyd-Jones M, Papaioannou D. Vitamin K to prevent fractures in older women: systematic review and economic evaluation. Health Technol Assess. 2009 Sep;13(45):iii-xi, 1-134.
Fang Y, Hu C, Tao X, Wan Y, Tao F. Effect of vitamin K on bone mineral density: a meta-analysis of randomized controlled trials. J Bone Miner Metab. 2012 Jan;30(1):60-8.
Vermeer C, Theuwissen E. Vitamin K, osteoporosis and degenerative diseases of ageing. Menopause Int. 2011 Mar;17(1):19-23.
Azuma K, Ouchi Y, Inoue S. Vitamin K: novel molecular mechanisms of action and its roles in osteoporosis. Geriatr Gerontol Int. 2014 Jan;14(1):1-7.
Hamidi MS, Gajic-Veljanoski O, Cheung AM. Vitamin K and bone health. J Clin Densitom. 2013 Oct-Dec;16(4):409-13.
Shah K, Gleason L, Villareal DT. Vitamin K and bone health in older adults. J Nutr Gerontol Geriatr. 2014;33(1):10-22.
Iwamoto J, Takeda T, Sato Y. Menatetrenone (vitamin K2) and bone quality in the treatment of postmenopausal osteoporosis. Nutr Rev. 2006 Dec;64(12):509-17.
Pearson DA. Bone health and osteoporosis: the role of vitamin K and potential antagonism by anticoagulants. Nutr Clin Pract. 2007 Oct;22(5):517-44.
Gundberg CM, Lian JB, Booth SL. Vitamin K-dependent carboxylation of osteocalcin: friend or foe? Adv Nutr. 2012 Mar 1;3(2):149-57.
Bügel S. Vitamin K and bone health in adult humans. Vitam Horm. 2008;78:393-416.
Booth SL. Vitamin K status in the elderly. Curr Opin Clin Nutr Metab Care. 2007 Jan;10(1):20-3.
Shea MK, Booth SL. Update on the role of vitamin K in skeletal health. Nutr Rev. 2008 Oct;66(10):549-57.
Iwamoto J, Sato Y, Takeda T, Matsumoto H. High-dose vitamin K supplementation reduces fracture incidence in postmenopausal women: a review of the literature. Nutr Res. 2009 Apr;29(4):221-8.
Iwamoto J, Matsumoto H, Takeda T. Efficacy of menatetrenone (vitamin K2) against non-vertebral and hip fractures in patients with neurological diseases: meta-analysis of three randomized, controlled trials. Clin Drug Investig. 2009;29(7):471-9.
Iwamoto J, Sato Y. Menatetrenone for the treatment of osteoporosis. Expert Opin Pharmacother. 2013 Mar;14(4):449-58.
Cranenburg EC, Schurgers LJ, Vermeer C. Vitamin K: the coagulation vitamin that became omnipotent. Thromb Haemost. 2007 Jul;98(1):120-5.
Guralp O, Erel CT. Effects of vitamin K in postmenopausal women: mini review. Maturitas. 2014 Mar;77(3):294-9.
In response to
Open Thread, Aug. 22 - 28, 2016
Saw the site mentioned on Breibart:
Link: http://www.breitbart.com/tech/2016/03/29/an-establishment-conservatives-guide-to-the-alt-right/
Money Quote:
...Elsewhere on the internet, another fearsomely intelligent group of thinkers prepared to assault the secular religions of the establishment: the neoreactionaries, also known as #NRx.
Neoreactionaries appeared quite by accident, growing from debates on LessWrong.com, a community blog set up by Silicon Valley machine intelligence researcher Eliezer Yudkowsky. The purpose of the blog was to explore ways to apply the latest research on cognitive science to overcome human bias, including bias in political thought and philosophy.
LessWrong urged its community members to think like machines rather than humans. Contributors were encouraged to strip away self-censorship, concern for one’s social standing, concern for other people’s feelings, and any other inhibitors to rational thought. It’s not hard to see how a group of heretical, piety-destroying thinkers emerged from this environment — nor how their rational approach might clash with the feelings-first mentality of much contemporary journalism and even academic writing.
Led by philosopher Nick Land and computer scientist Curtis Yarvin, this group began a ..."
I wasn't around back in the day, but this is nonsense, right? Nrx didn't start on lesswrong, yeah?
NRx emerged from some of the ideas that also coalesced into LW, but their aims couldn't be more different. A core item of the LW philosophy is altruism; NRx is systematized hatred.
Also, it being on Breitbart should be enough indication that its version of events is not to be trusted.
In response to
August 2016 Media Thread
Fiction Books Thread
I'm halfway through Italo Calvino's Cosmicomics. They're science-based creation myths, and they're breathtaking.
In response to
Open Thread, Aug. 1 - Aug 7. 2016
Elo has 145 negative votes for the past month. This is getting ridiculous. What's Eugine trying to prove?
Have you spent time with people practicing Radical Honesty? I didn't get how it worked from reading articles about it but in practice the folks in that community are quite nice.
No such community exists near me.
In response to
Open Thread, Aug. 1 - Aug 7. 2016
To illustrate the topic I wish to present, I'll quote a review for Harry Potter and the Cursed Child, which complains that
In Rowling’s novels, characters deliver a mix of clever repartee and thudding exposition. Here Thorne [...] defaults to the latter. The result is a play that fails to utilize the most elementary of playwright’s tools: subtext. Characters say exactly what they feel, explain exactly what is happening, and warn about what they’re going to do before they do it.
My everyday failure to handle indirect statements may relate to this (as well as the disagreements I've had with literature majors, and my own difficulties when writing): I have no patience for subtext. People saying exactly what they feel is the way I wish the world worked. Is there something wrong with me?
In response to
August 2016 Media Thread
Fiction Books Thread
Harry Potter and the Cursed Child is available now. I devoured the script in four hours and I will only say: it's powerful and beautiful.
In response to
Should we enable public binding precommitments?
Example: election campaign promises should be enforceable upon victory.
In response to
July 2016 Media Thread
Music Thread
I'm happy to have found minimal music. It reflects perfectly the way my head sounds on the inside. Main examples:
https://www.youtube.com/watch?v=kAzhzEjkdcI
View more: Next
= b715d02e85f7b3b4ae65ca3d3e450868)
Subscribe to RSS Feed
= f037147d6e6c911a85753b9abdedda8d){kind=logo}
Upvote post for those who have been hit by collateral damage in the Elo / Nier war, as it happened to me. I promise to upvote everyone who writes under this something that is not controversial.
If the problem is the sockpuppet army, while coders create a systematic solution, the community can help and show that the army of goodwilling men and women are stronger than any puppet master.
Make LW nice again.