You think that the danger of sex is biological and that this has been vanquished by vaccines, condoms, etc. In reality, most of the power of sex to harm is social, emotional, and psychological.
I think what diegocaleiro is saying is that these social and emotional factors are adaptations that evolved due to the biological dangers. Now that the biological dangers are mostly gone, the adaptations are unnecessary and even harmful. So inasfar as we can consciously influence the social and psychological factors, we would benefit from changing them to promote more sex.
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I'm not a medical professional either, but...
Except in the specific cases of microbes that target the immune response, wouldn't you expect to see things like an elevated white blood cell count in patients suffering from a pathogen, even if the specific pathogen was not well recognized or understood? In other words, you would see the symptom in a blood test even if you didn't know exactly how to look for the pathogen.
If the pathogen reproduces slowly (the pathogen that causes TB might be one such) or has some way of hiding from the immune system or is one of those viruses (e.g., the herpes family) that get into cells and tend to remain dormant for long intervals, then they can be very hard to detect and will certainly not show up in a WBC. I saw news reports earlier this year about evidence that some cases of obesity are caused by gut microbes not previously regarded by, e.g., doctors and society as being pathogenic.