Well, there has not been a nuclear war yet (excluding WWII where deaths from nuclear weapons were tiny in proportion), climate change has only been a known risk for a few decades, and progress is being made with electric cars and solar power. Things could be worse. Instead of moaning, propose solutions : what would you do to stop global warming when so much depends on fossil fuels?
On a separate note, I agree with the kneejerk reactions, but its a temporary cultural thing, caused partially by people basing morality on fiction. Get one group of people to watch GATTACA and another to watch Ghost in the shell, and they would have very different attitudes towards transhumanism. More interestingly, cybergoths (people who like to dress as cyborgs as a fashion statement) seem to be pretty open to discussions of actual brain-computer interfaces and there is music with H+ lyrics being realeased on actual record lables and brought by people who like the music and are not transhumanists... yet.
In conclusion, once enhancement become possible I think there will be a sizeable minority of people who back it - in fact this has allready happend with modafinil and students.
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If you think helping humanity is (in long term) a futile effort, because humans are so stupid they will destroy themselves anyway... I'd say the organization you are looking for is CFAR.
So, how would you feel about making a lot of money and donating to CFAR? (Or other organization with a similar mission.)
How cool, I've never heard of CFAR before. It looks awesome. I don't think I'm capable of making a lot of money, but I'll certainly look into CFAR.
Edit: I just realized that CFAR's logo is at the top of the site. Just never looked into it. I am not a smart man.