All of Alex K. Chen (parrot)'s Comments + Replies

Related - https://x.com/TOEwithCurt/status/1887905485120000198

FWIW it's said that a lot of people in major AI labs like the idea of "playing God"

"* this is why vocab can be a good IQ test: word use frequency is the original power law, and because you have been exposed to many more words than you consciously know, and how many of those words 'stick' will reflect your intelligence's efficiency at learning from 1 or 2 uses of a word, and thus provide a good proxy"

It's still a weird efficiency, especially b/c it can be "gamed" by studying for SATs or by midwit infovoreautists who don't have high working memory.

2Steven Byrnes
It’s not obvious to me that the story is “some people have great vocabulary because they learn obscure words that they’ve only seen once or twice” rather than “some people have great vocabulary because they spend a lot of time reading books (or being in spaces) where obscure words are used a lot, and therefore they have seen those obscure words much more than once or twice”. Can you think of evidence one way or the other? (Anecdotal experience: I have good vocabulary, e.g. 800 on GRE verbal, but feel like I have a pretty bad memory for words and terms that I’ve only seen a few times. I feel like I got a lot of my non-technical vocab from reading The Economist magazine every week in high school, they were super into pointlessly obscure vocab at the time (maybe still, but I haven’t read it in years).)
gwern142

And yet, despite the SAT being so studied for, it remains a pretty good IQ test overall, and SAT-V or the GRE verbal parts OK. I think that's because there are so many words (500k+ in English, and the GRE-V has no compunction about mining the obscurest just to f--- with you), and you would have to study so many in order to meaningful inflate your scores (because after all, while there may be only a hundred 'vocab words' on any given SAT test, you don't know which hundred). Let's see... Here's an interesting-looking reference: "How Many Words Do We Know? Pr... (read more)

Timothy Bates: "New finding: Rationality is what IQ tests measure."

https://x.com/timothycbates/status/1873031064039387560

2Viliam
If that's true, how do they explain Mensa, or all those smart people who believe in religion, homeopathy, etc? My guesses: * the human average is horribly low, IQ 130 is still pretty stupid, rationality starts maybe at IQ 160 * irrational high-IQ people are rare but visible; you mostly don't notice rational people unless they want it

Can't CoT's be what makes RL safe, however? (if you force the reasoner to self-limit under some recursion depth when it senses that the RL agent might be asking for so much that it makes it unsafe)

Answer by Alex K. Chen (parrot)10

Has anyone tried OneSkin/does it actually do what it claims? It acts on a mechanism independent from tretonin.

Could it be a good idea to enable a file uploading feature to LessWrong? (eg a file uploading feature of PDFs or certain images/media]. Could help against link rot, for example (and make posts from long ago last longer - I say this as someone who edits old posts to make them timeless).

3niplav
I guess a problem here would be the legal issues around checking whether the file is copyright-protected.

Can't you theoretically use both CellPainting assays and light-sheet microscopy?

I mean, I did look at CellPainting assays a small amount of time ago and I was still struck by how little control one had over the process, and how it isn't great for many kinds of mechanistic interpretability. I know there's a Brazil team looking at use of CellPainting for sphere-based silver-particle nanoplastics, but there are still many concrete variables, like intrinsic oxidative stress, that you can't necessarily get from CellPainting alone. 

CellPainter can be used f... (read more)

How do they figure out what waveforms to use and at what frequencies on your brain? The ideal waveforms/frequencies depend a lot on your brainwaves and brain configuration

I've heard fMRI-guided TMS is the best kind, but many don't use it [and maybe it isn't necessary?]

Is anyone familiar with MeRT? It's what wave neuroscience uses, and is supposedly effective for more than just depression (there are ASDs and ADHD, where the effectiveness is way less certain, but where some people can have unusually high benefits). But response rates seem highly inconsistent... (read more)

1InquilineKea
https://pmc.ncbi.nlm.nih.gov/articles/PMC8122027/
-2ProgramCrafter
Presumably Fourier transform or its developments can be used. (After all, light speed is negligible at the scale we're considering.)

Every single public mainstream AI model has RLHF'd out one of the most fundamental facts about human nature: that there exist vast differences between humans in basic ability/competence and they matter.

2Viliam
Is there a simple way to jailbreak the models, such as asking them to talk about a hypothetical parallel universe which is exactly like ours (same biology, same history), except that in the parallel universe humans can have different abilities and competences?

Lucy Lai's new PhD thesis (and YouTube explainer) is really really worth reading/watching: https://x.com/drlucylai/status/1848528524790923669 and is more broadly relevant to people than most other PhD theses [esp on the original subject of making rational decisions under constraints of working memory].

How about TMS/tFUS/tACS => "meditation"/reducing neural noise?

Drastic improvements in mental health/reducing neural noise & rumination are way more feasible than increasing human intelligence (and still have huge potential for very high impact when applied on a population-wide scale [1]), and are possible to do on mass-scale (and there are some experimental TMS protocols like SAINT/accelerated TMS which aim to capture the benefits of TMS on a 1-2 week timeline) [there's also wave neuroscience, which uses mERT and works in conjunction with qEEG, but ... (read more)

It's one of the most important issues ever, and has a chance of solving mass instability/unhappiness caused by wide inequality in IQs in the population, by giving the less-endowed a shot to increase their intelligence.

tFUS could be one of the best techniques for improving rationality, esp b/c [AT THE VERY MINIMUM] it is so new/variance-increasing and if the default outcome is not one that we want (as was the case of Biden vs Trump, and Biden dropping out was the desireable variance-increasing move) [and is the case now among LWers who believe in AI doom], we should be increasing variance rather than decreasing it. tFUS may be the avenue for better aligning people's thought with actions, especially when their hyperactive DMN or rumination gets in the way of their ability... (read more)

Why is thing IQ measuring mostly lognormal

Worth following for his take (and YouTube videos he is creating): https://x.com/jacobrintamaki

[he's creating something around this]

What are your scores on the US Economic Experts Comparison (Interactive Matrix)?

https://www.kentclarkcenter.org/economist-comparison-interactive-matrix/

How about people who just don't "give a fuck", are Nishkama Karma, and maintain emotional composure even in times when others doubt them/do not believe them (knowing that the end is what matters).They are graceful on the inside, and maintain internal composure in the face of chaos, but others may view their movements as ungraceful particularly b/c they have the sense (and enough of a reality distortion field) to "make the world adapt to them", rather than "adapt to the world" (if they succeed, they make the world adapt to them such that the world around th... (read more)

Wow, and Mexico's fertility rate just plunged to 1.82

Isn't that a non-disparagement clause, not a NDA?

This is a very promising start on some thesis (that could go further into the theory of computation/sid mani content/https://lifeiscomputation.com/), but the "intelligence growth curves" are not very intuitive. I wager that dimensionality is more important than number of elements in determining intelligence growth curves and especially number of discontinuous jumps.

Why does F^4_65's intelligence peak out at such a low value at time 2040? Why does 's intelligence peak out at a lower value than equal-dimensional fields with fewer elements in them... (read more)

2niplav
Hm, I had kind of hoped that this post would be memory-holed/I could do a major rewrite/re-analysis, since I don't really endorse it that much anymore. I agree it's not very intuitive, and I'd want to re-run this with many many more samples over different dimensionalities (not just ~10), and then calculate some statistics on the resulting data. (A little problem is that the version of the diamond-square algorithm I've written is O(2d) in the number of dimensions, which means I can't collect that many samples of different spaces for high dimensions). But this is also not ideal, because the values produced by the diamond-square algorithm are way too normally distributed—it's not the case that most algorithms are okay, and some are better; most learning architectures/possible minds are absolute garbage, with few great ones thrown in. The thing that IQ is measuring is probably lognormal, and the values looked at here aren't. But even that is not good, because using a metric-ish space instead of a tree-like structure is the wrong way of going about it, but that'd be a bit cumbersome to do, and I don't have steam for it, so I don't. ¯\(ツ)/¯

Has anyone tried Visia skin analysis to get feedback loops on skinhealth? (they reveal WAY more than just pictures) The problem with camera images is that visible light doesn't capture fine lines or wrinkles. My skin SEEMS to look as perfect as that of a 12-year old on the outside, but there is some small amount of wrinkling under my eyes that a visia reveals (which is why this thread prompted me to finally get dermatica tretonin) 

Collagen peptides also can help increase collagen synthesis and relieve fine lines (it's my biggest pet peeve b/c I can't ... (read more)

Newt Gingrich started out as an environmentalist (and a former member of the Sierra Club), but later turned away from it.

Even after he left congress, he still had some sympathy for environmental issues, as he wrote the book "Contract with Earth" (with an EO Wilson forward). 

Newt can be surprisingly high openness - a person oriented towards novelty can be pro-drilling (accel), pro-geoengineering, and pro-environment (which can be decel), and maybe not reconcile the two together in the most consistent way. He has been critical of both parties on climate... (read more)

Bill Frist, the former Republican Senate Majority Leader under Bush (even though he had a low score by the partisan/zero compromises LCV), is now chairman at the Nature Conservancy (it's even his LinkedIn profile header) and frequently speaks out on environment and climate change issues. His kind of Republicanism is now way out of vogue.

https://www.tennessean.com/story/news/2022/08/16/tenneessee-former-senator-bill-frist-elected-chair-nonprofit-nature-conservancy/10328455002/

https://www.linkedin.com/posts/billfristmd_nature-conservation-activity-7114961629... (read more)

No one mentioned Remnote? It's the one Roam replacer that seems to beat Roam on many of the things it was good at. 

I way prefer remote storage, having lost a hard drive before, so I don't like Obsidian much. 

Related "As stated, one of the main things I make-believe is true is the overlighting intelligence with which I align myself. I speculate that I am in a co-creative relationship with an intelligence and will infinitely superior to my own. I observe that I exist within energetic patterns that flow like currents. I observe that when I act in alignment with these subtle energetic currents, all goes well, desires manifest, direction is clear, ease and smoothness are natural. I observe that I have developed a high degree of sensitivity to this energy, and that ... (read more)

It depends on how processed the PUFA is - many PUFAs in processed foods are highly heated up. Processing PUFAs in high heat is what causes peroxidizeable aldehydes/acrolein/9-HNE/advanced lipid peroxidation end-products (ALEs)/etc

But PUFAs in soybeans (or sunflower seeds w/o extra procesing) themselves are way less likely to be bad, and this is what the epidemiological evidence hints at.

For whatever reason, PUFAs are VERY strongly protective against heart disease (b/c they lower LDL) and insulin resistance. These are the leading causes of death on western ... (read more)

2mako yass
This seems to be talking about situations where a vector of inputs has an optimal setting at extremes (convex), in contrast to situations where the optimal setting is a compromise (concave). I'm inclined to say it's a very different discussion than this one, as an agent's resource utility function is generally strictly increasing, so wont take either of these forms. The optimal will always be at the far end of the function. But no, I see the correspondence: Tradeoffs in resource distribution between agents. A tradeoff function dividing resources between two concave agents (t, where h is the hoard being divided between them,  ta,b,h(r)=Ua(r)+Ub(h−r)) will produce that sort of concave bulge, with its optimum being a compromise in the middle, while a tradeoff function between two convex agents will have its optima at one or both of the ends.

Does Germany have a lot of food/MP testing companies? Germany seems highly represented in analytical chemistry, as I saw from the SLAS2024 conference.. (for all those people who complain about "lack of innovation" in Europe, they're all underrating analytical chemistry). This conforms to stereotypes about Germans and precision..

(and the culture of Germany is WAY more amendable to eco-consciousness/environmental health than the culture of America)

It would be nice (even in fringe cases) to have one country/area dedicated to being microplastic/pollution free ... (read more)

Isn't having boundaries also partly to do with full on consent (proactive and retroactive) with your implied preferences being unknown?

Consent is tricky because almost no one who isn't unschooled grows up consenting to anything. People grow used to consenting to things that make them feel unhappy because they don't know themselves well enough, and they trap themselves into structures that punish you for dropping out or for not opting into anything. In that sense, the system does not respect your own boundaries for your own self autonomy - your actions don'... (read more)

1Chipmonk
I'd like to reply to your comment but I didn't understand your first sentence

multiscale entropy

netlify/vercel/heroku/shinyapps/fleek (find cool associated apps!) + replit

github 

modal/EC2/docker

photonic computing

Are exotic computing paradigms (ECPs) pro-alignment?

cf https://twitter.com/niplav_site/status/1760277413907382685

They are orthogonal to the "scale is all you need" people, and the "scale is all you need" thesis is the hardest for alignment/interpretability

some examples of alternatives: https://www.lesswrong.com/posts/PyChB935jjtmL5fbo/time-and-energy-costs-to-erase-a-bit, Normal Computing, https://www.lesswrong.com/posts/ngqFnDjCtWqQcSHXZ/safety-of-self-assembled-neuromorphic-hardware, computing-related thiel fellows (eg Thomas Sohmers, Tapa Ghosh)

[this is... (read more)

Have you seen smartairfilters.com?

I've noticed that every air purifier I used fails to reduce PM2.5 by much on highly polluted days or cities (for instance, the Aurea grouphouse in Berlin has a Dyson air purifier, but when I ran it to the max, it still barely reduced the Berlin PM2.5 from its value of 15-20 ug/m^3, even at medium distances from Berlin). I live in Boston where PM2.5 levels are usually low enough, and I still don't notice differences in PM [I use sqair's] but I run it all the time anyways because it still captures enough dust over the day

6Nathan Helm-Burger
Sounds like you use bad air purifiers, or too few, or run them on too low of a setting. I live in a wildfire prone area, and always keep a close eye on the PM2.5 reports for outside air, as well as my indoor air monitor. My air filters do a great job of keeping the air pollution down inside, and doing something like opening a door gives a noticeable brief spike in the PM2.5. Good results require: fresh filters, somewhat more than the recommended number of air filters per unit of area, running the air filters on max speed (low speeds tend to be disproportionately less effective, giving unintuitively low performance).
3Thomas Kwa
Yes, one of the bloggers I follow compared them to the PC fan boxes. They look very expensive, though the CADR/size and noise are fine. My guess is Dyson's design is particularly bad. No way to get lots of filter area when most of the purifier is a huge bladeless fan. No idea about the other one, maybe you have air leaking in or an indoor source of PM.

Using size-1 piksters makes you really aware of all the subtle noise that your hidden plaque is gives your mind (I noticed they cleared up plaque un-reachable by floss+waterpiks+electric toothbrushes.. the first step to alignment/a faithful computation is reducing unnecessary noise (you notice this easily on microdoses of weed/psychedelics)

It's a pareto-efficient improvement to give all alignment researchers piksters to eliminate this source of noise (align the aligners first - reducing unnecessary noise is always the first step to alignment [and near-term... (read more)

What are some strategies you use to "reduce the hit" when you're about to take in potentially bad news? This is important b/c it's sometimes important to face up "bad news" earlier rather than later, and there is social loss in some people not being able to face it until it's too late, esp b/c some kinds of "bad news" aren't as incorrigible as they may initially appear (just that you need out-of-distribution strategies to make the proper amends)

[some examples of bad news: irreversible data loss, cancer diagnosis, elevated epigenetic age, loss of important ... (read more)

Do you think there are many similar threads between shock value, surprisal, and awe? Like, are there many common threads - both neurologically and sociologically?

Totalitarian societies use "awe" as a tool of control.

Did awe evolve from "something more primitive" into the complex emotion it is today? What is the simplest animal species that can feel something akin to awe? Jane Goodall wrote that even chimpanzees can feel "awe" from a waterfall, and some cetacean experts have mentioned that whales/elephants can pause at events humans might react with awe to.... (read more)

It's worth mentioning that (many) autistic people are often better at not getting into higher layers of simalucra that cause them to be trapped by maze-dom.

[SBF is an obvious counterexample]

BTW the opposite of mazedom is Newscience.org

Microplastics (and pollution - both mimetic and actual) wreck boundaries by intercalcating between boundaries/cell membranes and reducing the integrity of the boundary. To reinforce proper boundaries, it's important to maintain the organism's overall health (eg deuterated PUFAs like RT-011 help reduce oxidative stress on polyunsaturated fatty acids in the cell membrane).

[when the integrity of boundaries is weakened, the organism's channel capacity is reduced by the extra noise].

https://studio.ribbonfarm.com/p/boundary-intelligence

https://twitter.com/Sara_I... (read more)

Has anyone considered.. spiritual outliers?

ALSO outliers in neurodevelopmental trajectories/cross-correlations in how fast one region of their brain develops relative to another region of their brain.

[there was someone at USC who presented at https://web.cvent.com/event/82cd3c8a-5f63-4fb2-b394-b0b7feb49093/summary who had a talk on outliers at a more neurophysiological level]. Maybe not QUITE the level of outlier we're looking for, but more directionally so

19. Title: PoserDeep Isolation Forest Outlier Analysis of Large Multimodal Adolescent Neuroimaging Da... (read more)

1Mo Putera
Say more? (e.g. illustrative / motivating examples, related reading etc)

https://stream.thesephist.com/updates/1711563348

 

Neurable headphones could be one way of crowdsourcing value signals b/c they're so wearable

Hm there are other people like https://soulsyrup.github.io/  and @guillefix and Ogi

tFUS is a way of accelerating internal alignment (look up PropheticAI). As are the Jhourney jhana people (though people like me have so much DMN noise that tFUS is needed first). Look up 

https://stream.thesephist.com/updates/1711563348

 

Talk to https://www.linkedin.com/in/steven-pang-625004218/ ?

Better sensors/data quality is super-impt, esp b/c data quality from traditional EEG is very poor.

https://github.com/soulsyrup

Also https://sccn.ucsd.edu/~scott/canexp00.html

https://www.linkedin.com/in/erosmarcello?miniProfileUrn=urn%3Ali%3Afs_miniProfile%3AACoAAANRGXMBF8gD4oOTUH4MeBg4W0Nu4g12yZ8&lipi=urn%3Ali%3Apage%3Ad_flagship3_feed%3BNzoHK%2BruTH%2BRrm9SgKs9Pg%3D%3D

Neurable (cody rall reviewed it) has over-the-ear EEG (which can be used ... (read more)

I mean, is there a way to measure the quality of the forecasters into the predictions? As number of forecasters expands, you get lower quality of average forecaster. Like how the markets were extremely overconfident (and wrong) about the Russians conquering Kiev...

Another example of an ethyl version being potentially better: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827200/

Has anyone done a study on whether or not bacteria incorporate chlorotyrosine (or other damaged protens) into their proteins at first pass? This seems very doable.

We now know that oxidized DNA bases can be incorporated into the intestines of mouse DNA.

5bhauth
One issue is that a lot of lab processes can cause a little bit of chlorination. Here is a study looking at insect cuticle of insects raised without deliberate chlorine introduction; it found chlorotyrosine at ~0.02% mass content. Tyrosine is typically ~3.2% of protein residues.

This may be far future, but what do you think of Fanzors over CRISPRs?

Also Minicircles?

9kman
The smaller size of Fanzors compared to Cas9 is appealing and the potential for lower immunogenicity could end up being very important for multiplex editing (if inflammation in off-target tissues is a big issue, or if an immune response in the brain turns out to be a risk). The most important things are probably editing efficiency and the ratio of intended to unintended edits. Hard to know how that will shake out until we have Fanzor equivalents of base and prime editors.
3GeneSmith
I hadn't even heard of Fanzors before you mentioned them. Very interesting. So it's basically an endonuclease native to eukaryotes! After a brief search I haven't been able to find any papers in which it has been used as an editor. The best case scenario here would be that the cieling for editing efficiency and specificity for Fanzor-based editors would be higher than for CRISPR-based alternatives. I am unsure at the moment whether that's true, and we likely won't know for a little while. Minicircles are cool, but they just seem like... small plasmids? Granted I am not an expert on this topic and they definitely have advantages over SOME types of plasmids, such as those that contain CpG sequences, which can trigger TLR9 activation and get the immune system riled up. I mean they're great in the sense that a plasmid that doesn't contain bacterial genes and can fit in a delivery vector like an AAV are great. I just don't really see them as a separate category of thing we haven't had before.
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