If you haven't been aware, reddit's /r/nootropics is censoring the new synthetic nootropics that many people found useful. for example one of the newest nootropics with interesting science behind it is isrib. there are whole communities behind it because of the censorship on the main /r/nootropics subreddit https://reddit.com/r/isrib, etc. here is a youtube link explaining science behind it: 

There are new synthetic nootropics for memory enhancement, like isrib. Anybody familiar? I don't see it discusses here

Structural insights into ISRIB, a memory-enhancing inhibitor of the integrated stress response

The integrated stress response (ISR) regulates protein synthesis under conditions of stress. Phosphorylation of translation initiation factor eIF2 by stress-sensing kinases converts eIF2 from substrate to competitive inhibitor of its dedicated nucleotide exchange factor, eIF2B, arresting translation. A drug-like molecule called integrated stress re... (read more)