Thanks for the response.
I thought the following article does a good job of outlining some of the limitations of PRS for embryo selection:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527452/
Like any new (medical) technology, I think that it's important to consider the ethical implications. This doesn't mean that we shouldn't do it or allow it, but just that we should be thoughtful about it.
As for clinic success rates, I didn't mean to imply that "they don't mean anything". It's just that prospective patients should be aware that they can't alwa...
Great post. Thank you. Fertility doctor here and a supporter of ART (assisted reproductive technologies) in general. A few thoughts (although you touched on a few of these below, worth emphasizing in my opinion):
We don’t actually know that JK He accomplished what he said he did. He may have tried. But the results have not been independently verified. That would require genotyping the parents and children. So, premature to say that germline editing appears safe in humans.