All of Sable's Comments + Replies

Sable20

I'm really happy to hear that this helped! Remember, all models are wrong, but some are useful. This model is useful for me; use it as long as it is useful to you.

Sable20

This is awesome! I totally should have thought of it, thanks!

1Mo Putera
Thanks for compiling these quotes :) seemed too important not to make them at least somewhat actionable for myself, hence the checklist. 
Sable20

That's awesome that you're doing that research!

My biggest question is probably what the distribution looks like for people who get TMS for depression - how many of them are "cured" in the sense that they never need TMS again? How many need it again after a year? Two years? And so on.

1mu_(negative)
Took me a while to get back to this question. I didn't know the answer so I looked up some papers. The short answer is, knowing this requires long follow-up periods which studies are generally not good at so we don't have great answers. Definitely a significant number of people don't stay better. The longer answer is, probably about half of people need some form of maintenance treatment to stay non-depressed for more than a year, but our view of this is very confounded. Some studies have used normal antidepressant medications for maintenance, and some studies have tried additional rounds of TMS, both of which work really well. Up to a third of patients experience "symptom worsening" meaning that after an initial improvement from TMS, their symptoms actually get worse than when they started, but apparently more TMS can fix this in most people? I wasn't completely sure what they were saying here. So yeah, it isn't great. A lot of people need maintenance of some kind. This could very well correlate with whether your depression is the "life circumstances" kind or the "intrinsic brain chemistry" kind, not that we have a great handle on differentiating those two either. Furthermore, (1) there are a few modes of TMS therapy out there, including most notably the accelerated course, and there may be different relapse rates across these treatment modes. There is some handwaving that the accelerated course may be more effective in this regard but I don't think we know yet. And (2) another important issue with interpreting these data is that many of the studies are done on people who are treatment resistant, such as yourself. It's unclear how much the results translate to the general population of depressed people. Overall this is probably not a very satisfying answer, I don't really have the specialist inside view on this one. FYI the most targeted paper I found on this topic is the citation below. Note that it's from 2016. There is probably something more recent, I just d
Sable61

I do think there's something to that idea - physical injury and pain is a very universal and visible experience, whereas mental illness is difficult to parse for those who've never experienced it. I also think there's some sense in which 'treatment' and 'cure' are treated differently for mental and physical illness.

A doctor wouldn't just prescribe painkillers for a broken arm and call it a day because your symptoms have been dealt with; they'd want to actually fix the problem. Depression, on the other hand, doctors seem perfectly fine with merely mitigating the symptoms. Perhaps because that's all they're confident they can do?

Sable30

I didn't, but I'm not surprised your sister had that experience. It's a loud, repetitive noise going off next to your ear. My clinic offered me earplugs, which I didn't need, but perhaps your sister could have used?

Sable10

That would be useful.

I suppose their calibration might be cause for concern. You're with yourself all the time, so you've been witness to your own highs and lows, but others might only see your highs (for example, if you only leave your house when you're above 50%, their scale would bottom out at 50%).

Sable30

I would love to try psilocybin, but can't because of where I work. I have tried Ketamine and am now trying TMS, which are the two FDA-approved 'nuclear options', and have been seeing some success with them.

Sable10

That's really interesting! I'm no expert in neurology, so thanks for the heads up!

Sable30

True. I just happen to have the 'very hard to do anything' kind, so that's what I describe.

2cubefox
Have you considered trying psilocybin? The effects of depression are so bad that I wouldn't worry much about it not being legally available.
Sable20

I haven't thought much about how treatment fits in here. I've certainly felt both dimensions mentioned get better/reduced through treatment (having to solve less puzzles, having to solve puzzles for coarser/less granular actions).

Ultimately, 'curing' depression would be the equivalent of removing the app from your brain.

2ricardotkcl
I'm so sorry you're experiencing this.  It will improve.  This is a really fascinating analogy. Building on the analogy with how different treatments (talking therapies, exercise, pharmacological interventions) influence or remove the app would be a lovely way to develop this. Hang in there.
Sable10

Interesting. I'm glad that this resonates, and like the idea that what I described was a generic experience, which can be caused by various issues in the brain.

Sable10

The comments below do capture some of my thoughts. I also feel depression as a lack of motivation and general malaise and inability to care about things or feel pleasure.

But these are 

  1. difficult to explain to someone who's never felt, and
  2. subjective feelings, which don't always translate well through language.

The metaphor is meant to invite someone to think about what their life would be like if, in order to do anything, they had to slog their way through tedious effort for little to no reward. I claim that the result looks, externally, very much like d... (read more)

Sable30

I want to support this; the initial motivation behind Georgism is, in fact, the exact question of why poverty still exists when so much progress has been made - and the answer is that when private actors are allowed to monopolize natural resources (most importantly land), all the gains accruing from productivity increases and technology eventually go to them.

A UBI, as Eliezer suggests, is a band-aid to the problem, addressing the symptom but not the disease, and so long as land rents (economic rent) are monopolized, the disease continues unabated.

I don't k... (read more)

Sable20

Yup. That's where I learned about it. I was looking for the link too and couldn't find it. Thanks!

Sable30

I completely agree.

I have these moments every so often when I think to myself, "The entire MIT undergraduate curriculum is available for free online. ...why do we need college, exactly?"

And so on.

I have another post on my substack (I'll get around to posting it here at some point) about the kind of gains we should be making in educational technology, but haven't been.

Sable10

Thanks! I don't know if I'm the person to write that book, but I do agree it'd be a good idea.

Sable10

Thanks for the response!

I agree that the social services model is simultaneously good and bad. The issue stems from schools having to contend with two very different problems:

  1. How do they deal with children from poor backgrounds who don't want to learn? How do they deal with idiots, special needs students, assholes, troublemakers, etc.?
  2. How do schools deal with gifted children? How do they deal with students who are smarter or learn faster than their peers?

These kinds of students need very different kinds of environments to thrive.

Paul Graham is representati... (read more)

Sable10

I switched up my medications and I'm feeling a lot better now, although it being summer really helps. Everything is better when the world outside is warm and sunny!

I've been looking into trying Spravato (Ketamine) as well, although the bureaucracy to actually get to trying it is no joke.

Thanks for asking!

Sable20

Thanks, it's my first time linking to my own sequence. I fixed the link to the first post in it.

Sable31

I like your approach! The only caveat I have is that the students taking these requirements could be anywhere from 9-17ish, so they won't necessarily be able to investigate the tools and concepts in depth the way they might in a college course.

3FlorianH
I see there might be limits to what is possible. On the other hand, I have the impression often the limits to what the students can learn (in economics) come more from us teaching in absurdly simplified cases too remote from reality and from what's plausible so that the entire thing we teach remains a purely abstract empty analytical beast. While I only guess even young ones are capable of understanding the more subtle mechanisms - in their few individual steps often not really complicated! - if only we taught them with enough empathy for the students & for the reality we're trying to model. As you write, with as little math as absolutely necessary.
Sable*20

Curious to hear your thoughts on my sequence

I'm going through a theoretical redesign of American public education, and I'd appreciate the feedback from a teacher's perspective.

1ClareChiaraVincent
Yes, I will take a look! :) 
5rotatingpaguro
broken link
Sable40

I completely agree - often the hardest part of designing a system is what to do about willful defectors.

Hopefully some of this will become more clear as I keep posting, but the basic gist is that students have to be allowed to fail. We should make every effort to accommodate those who need help and rehabilitate those we can, but in the end if a student is determined to not learn/disrupt other students, they get failed and kicked out.

Sable11

If there are actual crimes going on, I'd imagine the police should be called.

If a student is genuinely acting in bad faith - attending a class and ruining it for their peers - then they should be removed from the class and sent to a counselor/social worker.

Otherwise, "disruptive" is a difficult thing to pin down when there's no actual instruction to be interrupting.

4cousin_it
The number of such students is larger than you think. But the more important question is what the social worker would do with the student - what tools would be available to them. Because by default the student will just disrupt another class tomorrow and so on. There isn't any magic method to make disruptive students non-disruptive; schools would love to have access to such magic if it existed.
Sable21

They both tend to limit my (already limited) tolerance for it and make it much harder, although the depression makes it harder in general while the anxiety only makes it harder in higher-stakes situations, such as at work with a boss.

Your post is another interesting perspective I haven't delved into as much as I'd like. It reminds me of the parts work some of my friends are fond of - taking something negative in one's brain and asking, "but how is this useful? What is it doing for me? What is this piece of me trying to protect me from?" and then running with the result.

I'll have to give it more thought.

2Chipmonk
Any updates?
2Chipmonk
yes yes this! The Coherence Therapy Institute case studies are great for this btw
Sable10

Fixed, thanks.

There's a joke in here about getting negatives wrong when depressed...

Sable10

You're welcome! I'm glad it was helpful.

I also just looked up monotropism - I haven't run across the term before - and was like, yeah, that seems about right for me.

Interesting.

Sable10

Call it...unintentionally intentional? It makes sense to me that the mechanisms between them are related in some sort of Unified Field Theorem of the Mind sort of way.

I also have mental metaphors involving thermal mass and emotions...

Huh.

Sable10

As a fellow procrastinator, I'm right there with you. I've found, for instance, that downers (alcohol, barbiturates, etc.) can allow me to be productive if anxiety is the cause of the procrastination, but if it's depression than the downers don't help at all.

1StartAtTheEnd
I find that stimulants help if the cause is depression, but that they don't if the cause is anxiety. Stimulants make anxiety worse (but it's not so simple - since stimulants also increase your confidence). But if you're anxious, then you crash even harder once the stimulants stop working, and you might release too much adrenaline, so that you become numb instead of "fired up". I also find that being in "flight or flight mode" doesn't help much against deadlines. You're alert, but not in a way which is good for thinking. For chores and physical work, stimulants are great, but you should take care not to overexert yourself, remember to drink water, and take care of your blood pressure.
Sable20

Sure - I'm always interested in hearing other perspectives.

What's your secret?

Is it yoga?

(I bet it's yoga.)

1yanni kyriacos
Haha no yoga. Some combination of the following: - Meta cognitive therapy + CBT with this guy for 4 years - Lots of exercise (resistance training and cardio) - Sleeping lots - Found meaningful work + less a stressful industry - Stable relationship (monogomous) - This one is the curved ball, as I had already cured my OCD/GAD by the time I found it, but it definitely lifted my wellbeing a lot https://lochkelly.org/
Sable10

Not being very sad all the time is good for you, 10/10 recommend. 

Words to live by, right there.

I think everyone has some experience with anxiety and depression; the alternative is literally ataraxia. The distinctions come with things like, "is it transitory or chronic?" and "is it ruining your life?" I'm glad you're not in that state anymore, though.

With regards to anxiety, I've had thoughts recently along the same track; maybe I'll write them up at some point. It's almost a case of "the dose makes the poison" - some amount of anxiety is natural and can motivate you, but too much and it prevents you from doing anything.

Sable10

That's a fascinating description of your own state, and I hope you're working through it with your own resources.

For the post I was focusing more on a behaviorist approach to depression and anxiety, explaining what the resulting state/actions were by metaphor of how it felt internally, but I do also get the low mood and the feeling that everything is terrible.

I think I also get the 'lose the ability to perceive gradations of color' thing, which I think Scott's talked about before.

(I also had a nihilistic phase I grew out of. There's only so much 'depressed French people complaining' I can take!)

3StartAtTheEnd
Thank you! Yes, I am. I've grown bored of suffering, and the victim mentality has lost its appeal. At this point, even being negative is difficult for me. I'd have to put effort into taking myself seriously. But it's a balance. Being humble and allowing oneself to be small is also important as it increases the felt weight of the world. So I should allow myself to be "just human", i.e. a little weak. If I don't allow myself to be weak I won't be able to cry, and I won't be able to feel other peoples sympathy since I can't take it to heart. This is similar to being unable to feel other peoples compliments, which is the case when the standards you hold youself to are too high. Many people recommend stoicism or "not giving a fuck" to combat depression, I just want to warn against that. It's better to have courage (the ability to face ones fears) than it is to get rid of the fear. If "fear > courage" one should flip the inequality instead of destroying the entire equation by reducing both sides to 0 (nihilism). The correct alchemy here is "negative -> positive" not "negative -> nothingness". Reducing yourself to rubble leaves a lot of rebuilding work (nihilism -> meaning) Speaking of which, I have a friend who doesn't get embarrassed, she gets angry instead. I think there's a layer of responses. If she had not allowed herself to be angry, she'd go to the next layer, which is apathy. So the ordering goes from "receptive" to "jaded". Somebody does something which hurts you -> Brain protects you from pain, it's converted to sadness. -> The brain protects you from sadness, so it's converted to anger. -> The brain protects you from anger, so it's converted to apathy. This picture seems quite right: https://oasisenergyhealingcenter.com/wp-content/uploads/2016/03/Emotional-Energy-Compass-Graphic.jpg I guess I cope well with my issues because they tie into my hobbies so well. I'm not motivated by the idea that I will stop suffering once I improve my life, but experimenting o
Sable10

Thanks for sharing! I definitely like Scott's take on depression being a trapped prior.

When I'm depressed, sometimes a friend will make me go do stuff anyway and it usually makes me feel better, although I never expect it to make me feel better. Even when I know that it will.

Brains are weird.

Sable20

Thanks Anders! That means a lot, I really appreciate it. 

Thankfully I've seen my psychiatrist and I've switched to the next medication, which is doing a better job. I'm also looking into getting Ketamine treatment; I'll probably make a post about how that goes.

1Anders Lindström
Glad to hear you are doing better! Ok, that is an interesting route to go. Let "us" know how it goes if you feel for sharing your journey
Sable20

You may!

Zoloft managed the depression but not the anxiety, and Lexapro the anxiety but not the depression.

For what it's worth, I have zero expectation that anyone else would share my exact response to the medications; both have helped plenty of people in the past.

I think this post highlights some of the difficulties in transmitting information between people - particularly the case of trying to transmit complex thoughts via short aphorisms.

I think the comments provided a wealth of feedback as to the various edge cases that can occur in such a transmission, but the broad strokes of the post remain accurate: understanding compressed wisdom can't really be done without the life experience that the wisdom tried to compress to begin with.

If I was to rewrite the post, I'l likely emphasize the takeaway that, when giving a... (read more)

Sable10

I don't see this as a conscious choice people make to not solve the problems the institution they're a part of is supposed to address. I agree that many of the individuals within the institution are working in good faith and genuinely care.

The issue is that the incentives of the people are not the same as the incentives of the institution itself, which are to grow and attract more status and money, which happens when the problem is seen as harder and more important.

Yes, Climate Change is obviously not solvable by a few activists, but there's a finite amoun... (read more)

Sable10

I use homelessness as an example, but I believe the logic generalizes. You're right that in many cases, the incentives facing an institution aren't powerful enough to matter, or the people involved could/would just go do other things.

But there are also a lot of cases (see: almost all nonprofits) where people's jobs depend on the existence and salience of the problem, in which case I think the incentives do start to matter.

Sable10

While I haven't looked at the data lately, there are a lot of institutions in the US, as I use the term. Surely of the many social ills they address there are some that solvable/solved?

While I used ending homelessness as an example, the salience of an issue matters too. Climate change organizations receive lots of funding because their cause is seen as an important priority. If that changes, their funding dries up. So they have an incentive on the margin to overemphasize the importance of their associated problem - they benefit from the problem, while generally not solving it. Hence, commensalism.

2dr_s
There being a lot means resources are split and coordination may be harder, it doesn't make this easier. "Solving climate change" for example is nothing short of a monumental task that requires a complete overhaul of our current industrial system. No tiny group of activists will have the power to do that, they don't need to keep the problem around to stay relevant. And again, I think this widely misreads the people part of these things: these are people who mostly do want to solve the problems. They may not be optimal at it for various reasons and I get how incentives can create pressures that feed this sort of commensalism even without it being an intentional strategy, but it's absolutely not obvious to me how the process of "could solve the problem but doesn't" would manifest here. Perhaps you could argue it for some causes like e.g. animal rescues: lots of people have refuges for stray cats/dogs but their general motivation is probably just that they enjoy having the little fuzzballs around and helping them, so they're not really tackling the problem of stray animals head on with systematic spaying and neutering etc (though that is absolutely also a thing that they do). Also, I'd make a distinction between straight up commensalism and simple "are not cold utilitarian minimizers of suffering", because lots of people aren't the latter because they have other values they think are too important to trade off, so they don't just go at the problem as hard as they could, but that's not the same as keeping the problem intentionally around to justify their own work.
Sable10

Thanks! I've been pointed to them by others as well; it's a good example of an institution surviving the death of their problem.

I do think that the case underlines how important problems are for institutions, in a sort-of "exception that proves the rule" kind of way.

Sable10

They would need another problem to pivot to.

Also, I suspect that such a pivot on an institutional scale is difficult to pull off. People often prioritize altruistic work because they're passionate about a specific cause - maybe they were homeless in the past, or they were a cancer survivor, etc. That wouldn't necessarily translate.

4CronoDAS
It has been done. March of Dimes was originally an anti-polio organization; after the polio vaccines basically solved their problem, they generalized...
Sable10

This was well thought-out, thank you.

You're right about redefining the word/problem. I've been referring to this as "The Pivot" in my head.

It would still be better if we found a way to form institutions such that, once they had solved a problem, their resources were efficiently allocated to the solution of the next-most-pressing problem.

Sable20

Wait until you discover the world of Worm fanfiction (*cue evil laughter*).

1Neil
I'm doomed already. I've narrowly escaped a close encounter after reading a few chapters from at least one of them.  I may be cornered, however, but I shan't admit defeat. I've used a site blocker (haha!). This is what an actually pessimistic containment strategy looks like.  Check for the time being, minions of wildbow!
Sable10

Very possible.

I do suspect, though, that your friends at least have an internal process of analysis going even if they're not working. (I could of course be wrong.)

Sable31

Quite true, and I considered being more specific about the kinds of relationships I was talking about.

For the sake of brevity I omitted such relationships.

What I did try to emphasize was that a relationship doesn't have to be equal to be reciprocal. So long as each party is getting what they need out of it, it usually counts. In a parent/child relationship, for instance, the parent is/should be getting something valuable out of the relationship, even though that something isn't reciprocity or emotional support.

As you say, the reward might be seeing your junior/student/child grow up and succeed.

Sable10

I understand what you're saying. I wasn't familiar with the exact definitions of the political theory you cite.

I do think that it's reasonable to be bound by laws made before one was born, but only to a certain extent. Society changes over time, and over a long enough period of time I would argue - philosophically - that the society that passed the law is no longer the society I was born into. (And yet the law is still binding, because the law doesn't have an expiration date.)

That being said, thanks for the reply, and I appreciate the feedback!

Sable10

Fair, and I forgot about the term stuck prior (I think I've heard "trapped prior" before). Thanks!

Sable20

Great question.

You've got the basics - eat right, workout, sleep, etc., but just saying that isn't much help.

I've gotten a great deal out of habit chaining/trigger-action planning when used consistently; basically you create chains of actions that feed into one another so once you've started the chain, it takes no extra willpower to just keep following it to its conclusion.

For instance:

Wake up -> make breakfast -> get pills -> turn on sunlamp -> eat

is one, that makes sure I take my medication, eat breakfast, and get some light everyday (the lat... (read more)

2ErickBall
Excellent, I think I will give something like that a try
Sable30

A good point, and I agree. Part of my thinking on this topic, and the desire to write on it, was sparked by Scott and others' debate on what mental illness and sanity really are (how much of it is social, how much biological, etc.).

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