teageegeepea comments on The Dirt on Depression - Less Wrong
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I hadn't seen that about depression before, but that many chronic diseases are caused by yet undiscovered infectious agents has been around for a while. There is a good, very readable survey of the idea "Plague Time" by Paul Ewald written in 2000 and 2002 (http://www.amazon.com/Plague-Time-Germ-Theory-Disease/dp/0385721846/ref=sr_1_1?ie=UTF8&s=books&qid=1247684918&sr=8-1). The idea has been around for decades, but received a new boost when peptic ulcers were shown to be bacterial.
I haven't read the book, but the Atlantic had a series with Ewald & Greg Cochran on "New Germ Theory".