NancyLebovitz comments on Case study: Melatonin - Less Wrong

21 Post author: gwern 07 January 2010 06:24PM

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Comment author: NancyLebovitz 07 January 2010 07:35:06PM 0 points [-]

I've taken melatonin a few times-- it put me to sleep, though I think the onset of sleepiness was more like an hour after taking it. If I overrode the mild sleepiness, the melatonin's effect was lost,.

I've heard that people's natural production of melatonin declines with age, so there may be an age below which the pills don't make a huge difference for most people.

Comment author: gwern 09 January 2010 04:17:26PM 2 points [-]

I've taken melatonin a few times-- it put me to sleep, though I think the onset of sleepiness was more like an hour after taking it.

Sure, that's possible. Maybe your formulation simply took a long time; if I chew my pills, they act that much faster since they have that much more surface-area. No surprise there. I've seen time-delayed version as well.

I've heard that people's natural production of melatonin declines with age, so there may be an age below which the pills don't make a huge difference for most people.

This too is possible. I was reading some of the child studies, and an infant or young child produces impressive amounts; supplementing wouldn't do much. (I also tried some on one; he reported sleeping a little bit better but nothing he would've noticed if I hadn't asked him.)