AngryParsley comments on Case study: Melatonin - Less Wrong

21 Post author: gwern 07 January 2010 06:24PM

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Comment author: AngryParsley 07 January 2010 07:49:10PM *  3 points [-]

The fact that the study was on children certainly doesn't help the validity when applied to adults, but I think you're being overly risk-averse. Melatonin's mechanism of action is pretty well understood, and it occurs in the body already. The long-term effects would have to be very bad to outweigh the advantages of a regular sleep schedule and an extra hour of wakefulness every day. That's assuming melatonin works, of course.

Comment author: taryneast 04 June 2011 08:50:54PM 0 points [-]

Endorphins are chemicals that occur naturally in the body, with a mechanism that is pretty well understood. Yet taking opioids regularly is not good for you.

You cannot assume health-benefits simply because it already occurs in the body.

There may well be benefits, but they must be proved independently of simply understanding the natural mechanism.