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Eliezer_Yudkowsky comments on Case study: Melatonin - Less Wrong
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I am microdosing, 300mcg plain + 300mcg time-release, both from LEF. Currently trying doubling the time-release dosage to see if that works better. More than 400mcg up-front did not work well. In general, people trying melatonin are advised to try microdoses.
That's definitely something I noticed in the anecdotes: people with positive experiences seem to mention switching to <1mg doses, while people with negative experiences tend to mention >1mg doses and not experimenting.
I'm going to strengthen the language in my melatonin essay dealing with dosage, and add some reminders to myself to do more blind experiments with differing doses when I run out of my current melatonin pill mixes.
Any updates on this?
Not yet. My five-fold sleep experiment was originally supposed to be long done by now, but I put the lithium part on hold to run another long experiment, and so it hasn't finished yet. Hopefully I'll be able to start by 2014.