Case study: Melatonin

gwern

I discuss melatonin's effects on sleep & its safety; I segue into the general benefits of sleep and the severely disrupted sleep of the modern Western world, the cost of melatonin use and the benefit (eg. enforcing regular bedtimes), followed by a basic cost-benefit analysis of melatonin concluding that the net profit is large enough to be worth giving it a try barring unusual conditions or very pessimistic safety estimates.

Full essay: http://www.gwern.net/Melatonin

I discuss melatonin's effects on sleep & its safety; I segue into the general benefits of sleep and the severely disrupted sleep of the modern Western world, the cost of melatonin use and the benefit (eg. enforcing regular bedtimes), followed by a basic cost-benefit analysis of melatonin concluding that the net profit is large enough to be worth giving it a try barring unusual conditions or very pessimistic safety estimates.

Full essay: http://www.gwern.net/Melatonin

"It really amazes me that melatonin is available in any pharmacy," Bentley said. "It is a powerful hormone, and yet people don't realize that it's as 'powerful' as any steroid. I'm sure that many people who take it wouldn't take steroids so glibly. It could have a multitude of effects on the underlying physiology of an organism, but we know so little about how it interacts with other hormone systems."

A few cautions: Melatonin is considered generally safe for short-term use. However, there have been concerns about risks of bleeding (especially in people taking blood-thinners like warfarin). There also is increased risk of seizure, particularly in children with brain disorders.

http://www.webmd.com/vitamins-and-supplements/lifestyle-guide-11/natural-good-sleep-tips-on-melatonin-valerian

Also, risky for diabetics?

1wedrifid13y

Unless the quality of the remainder of the article uses an entirely different caliber of reasoning than what you have chosen to excerpt here it should be dismissed as drivel. The (by clear implication, anabolic) steroids that Bentley attempts to equate to melatonin have clear effects that need to be managed or accepted. There has been enough research and practical use of melatonin to reliably establish that whatever the effects of melatonin are they less significant than the effects of anabolic steroids.

1gwern13y

"So in conclusion: be afraid, be very afraid."

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Case study: Melatonin

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Case study: Melatonin

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