= 27d567bc2d48d9f40e9ccc20ea370b15)
timtyler comments on BHTV: Eliezer Yudkowsky & Razib Khan - Less Wrong
You are viewing a comment permalink. View the original post to see all comments and the full post content.
= 783df68a0f980790206b9ea87794c5b6)
Loading…= b715d02e85f7b3b4ae65ca3d3e450868)
Subscribe to RSS Feed
Powered by Reddit
= f037147d6e6c911a85753b9abdedda8d)
You are viewing a comment permalink. View the original post to see all comments and the full post content.
Comments (66)
Razib "reasoned from published research," too. Rushton doesn't have any PC points to lose. The main heuristic to keep in mind in discussing science is that most published findings are false, especially in popular fields. According to the paper Carl cited, the reported effect sizes are tiny, 0.1 to 1% of variance. The effect sizes are similarly small for genes affecting height; I don't know about replication. In the comments on the gnxp post Razib linked to, Ben G says that if you believed all the reported studies, but corrected for double counting from linkage disequilibrium, the total black-white differential effect is 3 points.
Tim did implicitly cite a replication, in the quote from wikipedia about CHRM2.
Theoretically, it is not so surprising that the effect sizes are small: if there is selective pressure for IQ and height, genes with large effects should be fixed, leaving the variation in genes of small effect.
Carl's paper said "most QTL effects may be much smaller than expected - not just 1% effect sizes but perhaps effects as small as .1%".
That is fine and surely perfectly expected. Most genes have little or nothing to do with intelligence - and so can be expected to have small effects on it.
The paper didn't say there were no larger effects caused by genetic variation. Genes associated with Fragile X syndrome, Tay-Sachs disease, Neurofibromatosis, etc are known to have larger effects.