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timtyler comments on BHTV: Eliezer Yudkowsky & Razib Khan - Less Wrong
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Down syndrome is not really "on the smallest chromosome". It results from an extra copy of chromosome 21. (22:48).
Right. I'm gonna have to find a balance between using bio-words and stuff I translate into normal speak on-the-fly. My first thought was to blurt out trisomy 21, and then I would have had to use the word non-disjunction. So I simply noted it was a problem with chrom 21 , and that is the smallest chrom so as to minimize dosage dependent effects.