I have to confess, if I had a lot of money to donate I'd find it very hard to swallow this advice whole and give it all to the SIAI; I'd feel like donating half to GiveWell or suchlike would be a "hedge" against the possibility that I fear UFAI for irrational reasons I haven't identified. However, I can't find a reason to think that uncertainty about my own sanity will plug into the math any differently than any other kind of uncertainty.
From Michael Anissimov on the Singularity Institute blog:
Thanks to generous contributions by our donors, we are only $11,840 away from fulfilling our $100,000 goal for the 2010 Singularity Research Challenge. For every dollar you contribute to SIAI, another dollar is contributed by our matching donors, who have pledged to match all contributions made before February 28th up to $100,000. That means that this Sunday is your final chance to donate for maximum impact.
Funds from the challenge campaign will be used to support all SIAI activities: our core staff, the Singularity Summit, the Visiting Fellows program, and more. Donors can earmark their funds for specific grant proposals, many of which are targeted towards academic paper-writing, or just contribute to our general fund
[Continue reading at the Singularity Institute blog.]