There's this Greg Egan story where you have people whose brains were forcibly modified so as to make them slaves to a cause, and they rediscover autonomy by first reasoning that, because of the superhuman loyalty to the cause which the brain modification gives them, they are more reliable adherents of the cause than the nominal masters who enslaved them, and from there they proceed to reestablish the ability to set their own goals.

The masters fail at 'Friendliness' theory. :)