A brief response: Yes, cryonic preservation causes all sorts of severe damage far beyond our current ability to overcome; all the damage discussed in this paper is well understood and widely discussed by cryonics practitioners. This paper doesn't seem to quite engage with the central contention of cryonics: that so long as the information that makes up memory and personality is preserved, future technology may find a way to repair the damage caused by cryopreservation. Two distinct paths to this end are widely talked about: molecular nanotechnology, and scanning/WBE. As far as I can tell, no argument is made in the paper that human cryopreservation causes information-theoretic death, and neither of these repair options are discussed at all. As a result, this paper, while it is vastly vastly ahead of the arguments made by other critics of cryonics, is some way behind the arguments already considered and answered by cryonics advocates.
As far as I can tell, no argument is made in the paper that human cryopreservation causes information-theoretic death, and neither of these repair options are discussed at all.
Cryonauts probably have enough information to reconstruct them to the point where childhood memories can be recovered. I don't think claiming otherwise would be a sensible critique. IMO, sceptics are better off sticking to looking at the costs.
Luke Parrish points me to what is clearly by far the most serious critique of cryonics ever written: a 57-page treatment by Evelina Martinenaite and Juliette Tavenier, presented as a 3rd semester project at Roskilde University in Denmark supervised by Ole Andersen.
Full paper