Disagree, there are successful instances of using karma in ways inconsistent with the rest of the site.

The most important counterexample here is Will Newsome's Irrationality Game post, where voting norms were reversed: the weirdest/most irrational beliefs were upvoted the most, and the most sensible/agreeable beliefs were downvoted into invisibility. Many of the comments in that thread, especially the highest-voted, have disclaimers indicating that they operate according to a different voting metric. There is no obvious indication that anyone was confused or malicious with regard to the changed local norm.