And that’s another thing: what the heck is going to be recorded? You need to measure the epigenetic state of every nucleus, the distribution of highly specific, low copy number molecules in every dendritic spine, the state of molecules in flux along transport pathways, and the precise concentration of all ions in every single compartment. Does anyone have a fixation method that preserves the chemical state of the tissue? All the ones I know of involve chemically modifying the cells and proteins and fluid environment. Does anyone have a scanning technique that records a complete chemical breakdown of every complex component present?
I think they’re grossly underestimating the magnitude of the problem. We can’t even record the complete state of a single cell; we can’t model a nematode with a grand total of 959 cells. We can’t even start on this problem, and here are philosophers and computer scientists blithely turning an immense and physically intractable problem into an assumption.
You’re just going to increase the speed of the computations — how are you going to do that without disrupting the interactions between all of the subunits? You’ve assumed you’ve got this gigantic database of every cell and synapse in the brain, and you’re going to just tweak the clock speed…how? You’ve got varying length constants in different axons, different kinds of processing, different kinds of synaptic outputs and receptor responses, and you’re just going to wave your hand and say, “Make them go faster!”
I’m not anti-AI; I think we are going to make great advances in the future, and we’re going to learn all kinds of interesting things. But reverse-engineering something that is the product of almost 4 billion years of evolution, that has been tweaked and finessed in complex and incomprehensible ways, and that is dependent on activity at a sub-cellular level, by hacking it apart and taking pictures of it? Total bollocks.
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