(2) is the interesting claim
So say something about it. Your whole comment is an attack on 1, but regardless of his word on whether or not thing slice vitrification is currently the best we can do, we KNOW fracturing happens with current brain preservation techniques. Liquid nitrogen is well below the glass transition, so fracturing is unavoidable.
Why should we expect fracturing/cracking to be 1 to 1?
If you're worried about the effects of cracking, you can pay for ITS. LN2 is only used because it is cheap and relatively low-tech to maintain.
If you ask me it's a silly concern if we're assuming nanorepair or uploading. Cracking is just a surface discontinuity, and it forms at a point in time where the tissue is already in a glassy state where there can't be much mixing of molecules. The microcracks that form in frozen tissue is a much greater concern (but not the only concern with freezing). The fact that vitrified tissue forms large, loud cracks is related to the fact that it does such a good job holding things in place.
In June 2012, Robin Hanson wrote a post promoting plastination as a superior to cryopreservation as an approach to preserving people for later uploading. His post included a paragraph which said:
This left me with the impression that the chances of the average cryopreserved person today of being later revived aren't great, even when you conditionalize on no existential catastrophe. More recently, I did a systematic read-through of the sequences for the first time (about a month 1/2 ago), and Eliezer's post You Only Live Twice convinced me to finally sign up for cryonics for three reasons:
I don't find that terribly encouraging. So now I'm back to being pessimistic about current cryopreservation techniques (though I'm still signing up for cryonics because the cost is low enough even given my current estimate of my chances). But I'd very much be curious to know if anyone knows what, say, Nick Bostrom or Anders Sandberg think about the issue. Anyone?
Edit: I'm aware of estimates given by LessWrong folks in the census of the chances of revival, but I don't know how much of that is people taking things like existential risk into account. There are lots of different ways you could arrive at a ~10% chance of revival overall:
is one way. But:
is a very similar conclusion from very different premises. Gwern has more on this sort of reasoning in Plastination versus cryonics, but I don't know who most of the people he links to are so I'm not sure whether to trust them. He does link to a breakdown of probabilities by Robin, but I don't fully understand the way Robin is breaking the issue down.