Lumifer comments on Lifestyle interventions to increase longevity - Less Wrong

120 Post author: RomeoStevens 28 February 2014 06:28AM

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Comment author: Lumifer 28 February 2014 06:33:50PM 2 points [-]

I personally cut my sugar intake from average (almost all from fruit by the way) to low. Consistent with his claims, my cholesterol (particularly LDL), triglycerides, and inflammatory markers fell dramatically

It is pretty clear there is WIDE individual variation in response to low carbs.

Low-carb and paleo forums are full of people who eat none or very little sugar and their lipid panels horrify mainstream doctors. See e.g. this or this.

Comment author: RomeoStevens 28 February 2014 08:45:54PM *  3 points [-]

My physical and mental performance improved when I went from VLC to a more moderate 150ish grams a day. My HDL, Triglyceride, and c-reactive protein numbers are great, and my total cholesterol is 220, which is right in the middle of the lowest risk group. We see pretty much every hunter gatherer group using tubers extensively, along with some fruit, as a carb base.

Comment author: Lumifer 28 February 2014 08:57:58PM *  2 points [-]

As far as I know going VLC will (typically) push both your LDL and HDL numbers up and will drastically lower your trigs. CRP is an inflammation measure, not part of the lipid panel.

We see pretty much every hunter gatherer group

You mean "We see pretty much every tropical hunter gatherer group". The Inuit/Eskimos obviously don't.

Comment author: RomeoStevens 01 March 2014 12:54:40AM 0 points [-]

The Inuit are a fairly large outlier in dietary makeup.

Comment author: RichardKennaway 19 March 2014 10:34:57AM 1 point [-]

Then it is all the more important to see how well or badly they do on their diet.

Comment author: waveman 19 March 2014 05:12:40AM 0 points [-]

My experience also. I formed the view, based on how I felt, that if I stayed on very low carb for much longer I would die, and a little bit of clean starch really made all the difference.

Comment author: waveman 19 March 2014 05:16:41AM 0 points [-]

Low-carb and paleo forums are full of people who eat none or very little sugar and their lipid panels horrify mainstream doctors.

Indeed. Healthy nutrition is not a matter of making a single choice, and individuals vary greatly in their responses to foods and drugs. (As one example: Green tea puts my blood pressure -up-, quite a lot, up to 12 hours later).

Lustig is making two main points I think:

  1. Carbs aint carbs. Fructose in its various forms is more like a saturated fat metabolically than a carb.

  2. The safe dose of fructose is pretty low for most people.

I haven't heard him advocate VLC.

The most important point is that carbs aint carbs.

Comment author: Lumifer 19 March 2014 03:40:04PM 0 points [-]

Carbs aint carbs

True, but then fats ain't fats as well -- different fatty acids have rather different effect on humans. Which is also true of different amino acids...