satt comments on What resources have increasing marginal utility? - Less Wrong
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For this reason, it seems to me that conjectures about people with no negative variants getting a 25 SD IQ gain are untestable. How would one distinguish such people from someone with a gain of only(!) 15 SD or 10 SD or even 7 SD, when the population available to norm IQ tests consists of only 7 billion people?
Create enough people at 15SD to test the 25SD subjects. :)
More seriously, this may be practically untestable but I think it's also the sort of thing which doesn't need to be tested - if we're ever in a position that the answer might matter, we have bigger fish to fry.