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Adele_L comments on Open Thread, Apr. 06 - Apr. 12, 2015 - Less Wrong
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Worth noting that you can easily obtain N-Acetyl Cysteine (e.g. from Amazon), which is an effective antidote to paracetamol toxicity (and the mechanism suggests it can be taken preventatively).
Perhaps good to have on hand as first aid, but are you suggesting taking more acetaminophen and trying to protectt your liver with the cysteine? Seems high risk, low reward if so.
Not suggesting anything like that at all, just a good and interesting thing to be aware of. Especially good to have on hand if you have kids, and I think it's probably good to take it with normal doses of paracetamol.
I don't think a mechanism suggesting that it can be taken preventatively is enough to suggest that it should be taken. It's a separate drug with it's own side effects.
Before taking it preventatively I would like to see studies that suggest that it's benefitial to take it in that fashion.