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Sjcs comments on Open Thread, Apr. 06 - Apr. 12, 2015 - Less Wrong
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This is incorrect. Normal paracetamol dosing is less than half the toxic dose of paracetamol, and it is an incredibly safe drug at these levels. Ibuprofen however has rare but well know side effects of gastric irritation, ulceration and life-threatening haemorrhage
Yes, that is the point. It is incredibly easy to go over double the normal, if you are irritated with symptoms. I know people who take three aspirin pills at once because they really want to throw a nuke on that hangover. A typical coldrex pill is 4 pills a day. It is far too easy to not even read it (it is OTC so "safe" right???? they would make it prescription if it was dangerous right???? <- this is a common logic used) and pop a pill every hour.
Unfortunately, paracetamol is included in some multi-drug combinations, so it's relatively easy to overdose by accident.