Ian_C. comments on But There's Still A Chance, Right? - Less Wrong
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The OPs acquaintance may have been right not to be convinced by the "1 in an incomprehensibly big number" argument. The domain in question (genes, insentient nature) operates by cause and effect, so there is no such thing as the million other paths evolution could have followed to make men and chimps different.
However the simple evidence of the similarity in the genomes should have been very convincing.